This research sought to find out factors that determine fruits and vegetables consumption among students of the Tamale College of Education. The study was a descriptive cross-sectional study. A sample of 384 students between 18-31years was selected from the level 100 and 200 students. 10 questionnaires were pretested on socio-demographic characteristics, basic knowledge on fruits and vegetables consumption, level of consumption of fruits and vegetables and the determinants of fruits and vegetables at the Tamale College of Education. Basic knowledge on fruits and vegetables consumption was scored on a scale of 0-10 with scores between 0-5 accorded as low knowledge while scores of 6-10 were accorded as high knowledge. Results from this study showed that 68.0% of the respondents displayed a high knowledge of the nutritional value of fruits and vegetables; however, daily consumption of fruits and vegetables was 43.8% and 38.8% respectively, this showed that level of consumption was low.