The purpose of the study was to analyse the influence of credit risk management practices on loan performance of Assinman Rural Bank (ARB), Central Region of Ghana. The design adopted for the study was descriptive survey design. In relation to the accessible population, the study considered all the 59 permanent staff within the six branches of the ARB. The census method was used to capture all the permanent staff within the institution. Questionnaire was the data collection instrument used for this study. The reliability coefficient of the instrument was 0.87, which was deemed appropriate and significant. Both descriptive and inferential statistics were used to analyse the data. The key findings that emerged from the study were that credit risk management practices of ARB have a significant and positive relationship to the bank’s loan performance. Furthermore, the bank’s credit risk management practices influence its loan performance significantly.