The main objective of the study was to determine how work-life balance policies and practices are carried out in the Tamale Teaching Hospital. Using a sex ratio of 1:1, the study involved 332 respondents. The data collection involved the use of questionnaire and face-to-face interviews. The kinds of work-life balance policies that were more practiced in the hospital were maternity leave, study leave and excuse duty leave. Excuse duty, free health screening, study leave and working from home had low mean values and were less practiced.