Abstract This study sought to investigate the factors influencing students’ choice of tertiary education in Sunyani Technical University. The study adopted quantitative method using descriptive survey. Questionnaire was the main instrument used to solicit primary data from the respondents. Two hundred (200) students of 2019/2020 academic year batch were selected using convenience sampling technique to participate in the study. Descriptive and inferential statistics were used to analyse the data collected. The study identified reputation of institution as a major factor influence respondent’s choice of tertiary institution and followed by parental factors. The least factor was peer and media influence respectively. The study also unraveled that subject combinations at Senior High School, personal interest, career desire, employment opportunities, recognition of the programme and academic records were factors influencing students’ choice of programme in tertiary education.